My husband was diagnosed with azoospermia. The product was recommended by an embryologist and a nurse at the IVF center. If it were up to the doctors, they would have gone straight to surgery. Compared to other brands, this product has twice the active ingredients, and we used just one box. Along with proper nutrition and exercise, there was some sperm production, which allowed for freezing, and we were told the sperm obtained was of good quality. We were hesitant at first, wondering if it would work, but it did—even hormone levels returned to normal.